Study: Heres Some Evidence That Switching Among Generic Levothyroxine Products Is OK
After 4 to 6 weeks of treatment, your doctor will check blood tests to monitor your thyroid. And your doctor may adjust your dosage of Synthroid if needed based on your lab results. Synthroid helps to bring your thyroid hormone levels back to a normal range. Synthroid is a synthetic form of a natural thyroid hormone called T4.
- During Synthroid treatment, your doctor will order blood tests to check your TSH level.
- It’s important to note that Synthroid and generic buy levothyroxine without prescription wholesale may each have different effects on your thyroid hormone levels.
- And the results of the study showed that there was no detectable gluten in the tablets.
- Both Synthroid and levothyroxine comes as tablets that are taken by mouth.
- Mylan, one of the biggest makers of generic drugs, said the order found that the inclusion of levothyroxine sodium on Florida’s negative drug formulary was an invalid exercise of authority.
For the most part, studies don’t show clear advantages of one type—brand name or generic—over others. But people’s experiences tell another story, with some describing feeling much better after changing from one formulation to another. This medication is also used to treat other types of thyroid disorders (such as certain types of goiters, thyroid cancer). Some limitations to the study included the observational nature of the analysis, as well as an inability to control for other factors that could influence absorption of the medication, like concomitant use of over-the-counter calcium. These are the most accurate medication prices at the time of publishing. Even prescribers who are completely comfortable with writing scripts for generics or biosimilars may have some reservations about switching patients who are stable on a brand-name drug to generic or switching from one generic to another.
Study: Here’s Some Evidence That Switching Among Generic Levothyroxine Products Is OK
The relative bioavailability of SYNTHROID tablets, compared to an equal nominal dose of oral levothyroxine sodium solution, is approximately 93%. T4 absorption is increased by fasting, and decreased in malabsorption syndromes and by certain foods such as soybeans. In addition, many drugs and foods affect T4 absorption [see DRUG INTERACTIONS]. In patients with severe longstanding hypothyroidism, start with a dose of 12.5 to 25 mcg per day.
Side effects of taking Synthroid, short and long-term
Off-label drug use is when a drug that’s approved for one use is used for a different one that’s not approved. And you may wonder if Synthroid is used for certain other conditions. Below is information on a use for Synthroid that’s not appropriate. For information on Synthroid’s history and the lack of clinical studies of this drug, see the “History of Synthroid” section just above. In addition, levothyroxine treatment has been shown to be safe and without many serious side effects.
What other drugs will affect Synthroid?
It is used to treat low thyroid hormone levels (hypothyroidism), which can be consequence of an enlarged thyroid gland, an injured thyroid gland, or thyroid cancer. First, it was retrospective, and drug choice was not randomly assigned. Hence, there may be a number of unknown and unmeasured confounders not accounted for that influence both drug assignment and patient outcomes. Second, whether the patient was taking generic LT4 or Synthroid was determined by prescription records in their chart, which may not reflect what they actually received from the pharmacy. In addition, for patients on generic LT4, the record of which manufacturer the LT4 came from was incomplete or missing for nearly half the cases.